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Abstract: treating eczema using the Dual Yellow laser

 

Interesting abstract about the treatment of Eczema with Copper Bromide technology. This opens new possibilities for the versatile Dual Yellow laser.

Title: Treatment of periorbital eczema using copper bromide laser in atopic dermatitis patients

Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine
Jong Hoon Kim,Jae Yong Sung, Hyun Jung Kim, Seung, Hun Lee

Atopic dermatitis (AD) is a common chronic inflammatory disease that presents a relapsing form of inflammation due to skin barrier interruption and allergic sensitization [1]. Histologic findings show dilated and tortuous vessels on the dermal papilla, which aggravate the inflammation by recruiting a number of immunoreactive factors then cause a vicious itching cycle [1]. Recently, vasoactive agents including vascular endothelial growth factor (VEGF), which lead to vessel dilatations and proliferations, are overexpressed in the lesions of AD [2, 3]. A therapeutic target to the vessel, thus, becomes an important method for stopping the chronic inflammations in AD [3].

We encountered two patients who have lichenifications on the periorbital areas caused by chronic AD and treated the areas using a copper bromide laser which is a new type of vascular laser with an output of 578-nm yellow light. A 26-yr-old Korean male patient visited our clinic with a 2-yr AD history of scaly erythematous patches over his whole body. A second 23-yr-old Korean male patient presented to our clinic with chronic AD. He had previously been treated with topical corticosteroids, topical pimecrolimus, antihistamines and moisturizers for 2 yr. However, inflammations and lichenifications on the periorbital area of both patients, referred to Dennie-Morgan folds, cannot be well controlled by the regular use of topical corticosteroids or calcineurin inhibitors combined with oral antihistamines and corticosteroids .

Two sessions of treatment using a 578-nm copper bromide laser (Plus YellowTM; Norseld, Adelaide, SA, Australia) at 6-week intervals were performed for both patients. Two passes of treatment were delivered to the bilateral periorbital area, with settings of 578-nm yellow light, 25J/cm2 and rapid pulse mode using a 1-mm hand-piece. The periorbital lesions of both patients were resolved by laser treatment and remained in an improved state one month after the final treatments In conclusion, 578-nm copper bromide laser treatments using yellow light are a good alternative option for the treatment of periorbital eczema in AD. However, further studies are required to understand the precise mechanisms of vascular laser treatment on AD.

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